Jeffrey M. Drazen, MD
Title Adjunct Professor
Institution Boston University School of Medicine
Department Medicine
Division Pulmonary, Allergy, Sleep & Critical Care Medicine
Address 715 Albany St, Dob
Boston, MA 02118
Telephone
Email
Publications
1. Drazen JM, Solomon CG, Greene MF. Informed consent and SUPPORT. N Engl J Med. 2013 May 16; 368(20):1929-31.
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2. Park JA, Sharif AS, Shiomi T, Kobzik L, Kasahara DI, Tschumperlin DJ, Voynow J, Drazen JM. Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2013 May; 304(10):L701-7.
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3. Malhotra A, Drazen JM. High-frequency oscillatory ventilation on shaky ground. N Engl J Med. 2013 Feb 28; 368(9):863-5.
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4. Curfman GD, Morrissey S, Drazen JM. Affirmative action in the balance. N Engl J Med. 2013 Jan 3; 368(1):73-4.
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5. Kohane IS, Drazen JM, Campion EW. A glimpse of the next 100 years in medicine. N Engl J Med. 2012 Dec 27; 367(26):2538-9.
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6. Drazen JM, Curfman GD, Baden LR, Morrissey S. Compounding errors. N Engl J Med. 2012 Dec 20; 367(25):2436-7.
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7. Drazen JM. Believe the data. N Engl J Med. 2012 Sep 20; 367(12):1152-3.
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8. Drazen JM. Transparency for clinical trials--the TEST Act. N Engl J Med. 2012 Aug 30; 367(9):863-4.
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9. Park JA, Sharif AS, Tschumperlin DJ, Lau L, Limbrey R, Howarth P, Drazen JM. Tissue factor-bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo. J Allergy Clin Immunol. 2012 Dec; 130(6):1375-83.
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10. Drazen JM. Asthma: The paradox of heterogeneity. J Allergy Clin Immunol. 2012 May; 129(5):1200-1.
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11. von Mutius E, Drazen JM. A patient with asthma seeks medical advice in 1828, 1928, and 2012. N Engl J Med. 2012 Mar; 366(9):827-34.
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12. Ring J, Akdis C, Behrendt H, Lauener RP, Schäppi G, Akdis M, Ammann W, de Beaumont O, Bieber T, Bienenstock J, Blaser K, Bochner B, Bousquet J, Crameri R, Custovic A, Czerkinsky C, Darsow U, Denburg J, Drazen J, de Villiers EM, Fire A, Galli S, Haahtela T, zur Hausen H, Hildemann S, Holgate S, Holt P, Jakob T, Jung A, Kemeny M, Koren H, Leung D, Lockey R, Marone G, Mempel M, Menné B, Menz G, Mueller U, von Mutius E, Ollert M, O'Mahony L, Pawankar R, Renz H, Platts-Mills T, Roduit C, Schmidt-Weber C, Traidl-Hoffmann C, Wahn U, Rietschel E. Davos declaration: allergy as a global problem. Allergy. 2012 Feb; 67(2):141-3.
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13. Wood AJ, Drazen JM, Greene MF. The politics of emergency contraception. N Engl J Med. 2012 Jan 12; 366(2):101-2.
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14. Drazen JM. A step toward personalized asthma treatment. N Engl J Med. 2011 Sep 29; 365(13):1245-6.
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15. Bäck M, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE. International Union of Basic and Clinical Pharmacology. LXXXIV: leukotriene receptor nomenclature, distribution, and pathophysiological functions. Pharmacol Rev. 2011 Sep; 63(3):539-84.
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16. Cozzi E, Ackerman KG, Lundequist A, Drazen JM, Boyce JA, Beier DR. The naive airway hyperresponsiveness of the A/J mouse is Kit-mediated. Proc Natl Acad Sci U S A. 2011 Aug 2; 108(31):12787-92.
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17. Dahlén SE, Dahlén B, Drazen JM. Asthma treatment guidelines meet the real world. N Engl J Med. 2011 May 5; 364(18):1769-70.
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18. Curfman GD, Morrissey S, Drazen JM. Prescriptions, privacy, and the First Amendment. N Engl J Med. 2011 May 26; 364(21):2053-5.
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19. Ingelfinger JR, Drazen JM. Patient organizations and research on rare diseases. N Engl J Med. 2011 Apr 28; 364(17):1670-1.
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20. Shiomi T, Boudreault F, Padem N, Higashiyama S, Drazen JM, Tschumperlin DJ. Lysophosphatidic acid stimulates epidermal growth factor-family ectodomain shedding and paracrine signaling from human lung fibroblasts. Wound Repair Regen. 2011 Mar-Apr; 19(2):229-40.
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21. Shiomi T, Tschumperlin DJ, Park JA, Sunnarborg SW, Horiuchi K, Blobel CP, Drazen JM. TNF-a-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):376-85.
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22. Bousquet J, Mantzouranis E, Cruz AA, AĂŻt-Khaled N, Baena-Cagnani CE, Bleecker ER, Brightling CE, Burney P, Bush A, Busse WW, Casale TB, Chan-Yeung M, Chen R, Chowdhury B, Chung KF, Dahl R, Drazen JM, Fabbri LM, Holgate ST, Kauffmann F, Haahtela T, Khaltaev N, Kiley JP, Masjedi MR, Mohammad Y, O'Byrne P, Partridge MR, Rabe KF, Togias A, van Weel C, Wenzel S, Zhong N, Zuberbier T. Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol. 2010 Nov; 126(5):926-38.
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23. Campion EW, Drazen JM. [Peer review journals in the digital age]. Arch Bronconeumol. 2010 Nov; 46(11):569-70.
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24. Curfman GD, Morrissey S, Drazen JM. Products at risk. N Engl J Med. 2010 Oct 28; 363(18):1763.
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25. Campion EW, Miller PW, Costello J, Duff E, Drazen JM. The Journal from 1812 to 1989 at NEJM.org. N Engl J Med. 2010 Sep 16; 363(12):1175-6.
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26. Curfman GD, Morrissey S, Drazen JM. Sibutramine--another flawed diet pill. N Engl J Med. 2010 Sep 2; 363(10):972-4.
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27. Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hebert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the Updated ICMJE conflict of interest reporting form. Croat Med J. 2010 Aug; 51(4):287-8.
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28. Campion EW, Scott L, Bowab C, Fleming S, Blizzard TJ, Lamb C, Easley TJ, Drazen JM. The New NEJM.org. N Engl J Med. 2010 Aug 12; 363(7):677-8.
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29. Park JA, Drazen JM, Tschumperlin DJ. The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J Biol Chem. 2010 Sep 24; 285(39):29817-25.
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30. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. N Z Med J. 2010 Jul 16; 123(1318):12-4.
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31. Drazen JM, Wood AJ. Don't mess with the DSMB. N Engl J Med. 2010 Jul 29; 363(5):477-8.
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32. Kazani S, Ware JH, Drazen JM, Taylor DR, Sears MR. The safety of long-acting beta-agonists: more evidence is needed. Respirology. 2010 Aug; 15(6):881-5; discussion 885-6.
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33. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Towards more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. Med J Aust. 2010 Jul 5; 193(1):7-8.
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34. Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: updated ICMJE conflict of interest reporting form. CMAJ. 2010 Jul 13; 182(10):E425.
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35. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van der Weyden MB, Zhaori G. Toward more uniform conflict disclosures--the updated ICMJE conflict of interest reporting form. N Engl J Med. 2010 Jul 8; 363(2):188-9.
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36. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. Dan Med Bull. 2010 Jul; 57(7):A4168.
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37. Drazen JM, de Leeuw PW, Laine C, Mulrow CD, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. Ann Intern Med. 2010 Aug 17; 153(4):268-9.
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38. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. JAMA. 2010 Jul 14; 304(2):212-3.
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39. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures--the updated ICMJE conflict of interest reporting form. Tidsskr Nor Laegeforen. 2010 Jul 1; 130(13):E1-2.
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40. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE Conflict of Interest Reporting Form. Chin Med J (Engl). 2010 Jul; 123(13):1621-2.
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41. Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures--the updated ICMJE reporting form for disclosure of potential conflicts of interest. Rev Med Chil. 2010 Jul; 138(7):801-3.
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42. Drazen JM, De Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. Natl Med J India. 2010 Jul-Aug; 23(4):196-7.
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43. Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, Horton R, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Towards more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. BMJ. 2010; 340:c3239.
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44. Kritek PA, Drazen JM. Clinical decisions. American Board of Internal Medicine maintenance of certification program--polling results. N Engl J Med. 2010 Apr 15; 362(15):e54.
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45. Drazen JM, Weinstein DF. Considering recertification. N Engl J Med. 2010 Mar 11; 362(10):946-7.
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46. Bousquet J, Kiley J, Bateman ED, Viegi G, Cruz AA, Khaltaev N, AĂŻt Khaled N, Baena-Cagnani CE, Barreto ML, Billo N, Canonica GW, Carlsen KH, Chavannes N, Chuchalin A, Drazen J, Fabbri LM, Gerbase MW, Humbert M, Joos G, Masjedi MR, Makino S, Rabe K, To T, Zhi L. Prioritised research agenda for prevention and control of chronic respiratory diseases. Eur Respir J. 2010 Nov; 36(5):995-1001.
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47. von Mutius E, Drazen JM. Choosing asthma step-up care. N Engl J Med. 2010 Mar 18; 362(11):1042-3.
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48. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform format for disclosure of competing interests in ICMJE journals. J Am Dent Assoc. 2010 Feb; 141(2):131-2.
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49. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform format for disclosure of competing interests in ICMJE journals. Ann Intern Med. 2010 Jan 19; 152(2):125-6.
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50. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform format for disclosure of competing interests in ICMJE journals. Med J Aust. 2009 Nov 2; 191(9):475-6.
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51. Uniform format for disclosure of competing interests in ICMJE journals. N Z Med J. 2009 Oct 30; 122(1305):12-4.
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52. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Uniform format for disclosure of competing interests in ICMJE journals. Lancet. 2009 Oct 24; 374(9699):1395-6.
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53. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Uniform format for disclosure of competing interests in ICMJE journals. CMAJ. 2009 Oct 27; 181(9):565.
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54. Drazen JM, Van der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Uniform format for disclosure of competing interests in ICMJE journals. N Engl J Med. 2009 Nov 5; 361(19):1896-7.
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55. Drazen JM, Van der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Uniform format for disclosure of competing interests in ICMJE journals. JAMA. 2010 Jan 6; 303(1):75-6.
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56. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Disclosure of competing interests. BMJ. 2009; 339:b4144.
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57. Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Uniform format for disclosure of competing interests in ICMJE Journals. Croat Med J. 2009 Oct; 50(5):427-8.
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58. Tantisira KG, Drazen JM. Genetics and pharmacogenetics of the leukotriene pathway. J Allergy Clin Immunol. 2009 Sep; 124(3):422-7.
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59. Curfman GD, Morrissey S, Malina D, Drazen JM. Health care reform 2009 at healthcarereform.nejm.org. N Engl J Med. 2009 Aug 13; 361(7):709-10.
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60. Curfman GD, Morrissey S, Drazen JM. Tobacco, public health, and the FDA. N Engl J Med. 2009 Jul 23; 361(4):402-3.
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61. Baden LR, Drazen JM, Kritek PA, Curfman GD, Morrissey S, Campion EW. H1N1 influenza A disease--information for health professionals. N Engl J Med. 2009 Jun 18; 360(25):2666-7.
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62. Drazen JM, O'Byrne PM. Risks of long-acting beta-agonists in achieving asthma control. N Engl J Med. 2009 Apr 16; 360(16):1671-2.
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63. Curfman GD, Morrissey S, Drazen JM. The Medical Device Safety Act of 2009. N Engl J Med. 2009 Apr 9; 360(15):1550-1.
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64. Hamel MB, Drazen JM, Epstein AM. The growth of hospitalists and the changing face of primary care. N Engl J Med. 2009 Mar 12; 360(11):1141-3.
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65. Drazen JM, Desai NR, Green P. Fighting on. N Engl J Med. 2009 Jan 29; 360(5):444-5.
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66. Curfman GD, Morrissey S, Greene MF, Drazen JM. Physicians and the First Amendment. N Engl J Med. 2008 Dec 4; 359(23):2484-5.
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67. Curfman GD, Morrissey S, Drazen JM. The FDA and tobacco regulation. N Engl J Med. 2008 Sep 4; 359(10):1056-7.
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68. Drazen JM, D'Agostino RB, Ware JH, Morrissey S, Curfman GD. Ezetimibe and cancer--an uncertain association. N Engl J Med. 2008 Sep 25; 359(13):1398-9.
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69. Morrissey S, Curfman GD, Drazen JM. Health of the nation--coverage for all Americans. N Engl J Med. 2008 Aug 21; 359(8):855-6.
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70. Curfman GD, Morrissey S, Drazen JM. Cardiac transplantation in infants. N Engl J Med. 2008 Aug 14; 359(7):749-50.
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71. Drazen JM, Morrissey S, Curfman GD. Guns and health. N Engl J Med. 2008 Jul 31; 359(5):517-8.
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72. Curfman GD, Morrissey S, Drazen JM. Why doctors should worry about preemption. N Engl J Med. 2008 Jul 3; 359(1):1-3.
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73. Curfman GD, Morrissey S, Annas GJ, Drazen JM. Peer review in the balance. N Engl J Med. 2008 May 22; 358(21):2276-7.
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74. Schwartz RS, Curfman GD, Morrissey S, Drazen JM. Full disclosure and the funding of biomedical research. N Engl J Med. 2008 Apr 24; 358(17):1850-1.
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75. Drazen JM, Jarcho JA, Morrissey S, Curfman GD. Cholesterol lowering and ezetimibe. N Engl J Med. 2008 Apr 3; 358(14):1507-8.
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76. Curfman GD, Morrissey S, Drazen JM. Handgun violence, public health, and the law. N Engl J Med. 2008 Apr 3; 358(14):1503-4.
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77. Hunter DJ, Khoury MJ, Drazen JM. Letting the genome out of the bottle--will we get our wish? N Engl J Med. 2008 Jan 10; 358(2):105-7.
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78. Curfman GD, Morrissey S, Drazen JM. Physicians and execution. N Engl J Med. 2008 Jan 24; 358(4):403-4.
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79. Curfman GD, Morrissey S, Drazen JM. A pivotal medical-device case. N Engl J Med. 2008 Jan 3; 358(1):76-7.
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80. Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, Gibson P, Ohta K, O'Byrne P, Pedersen SE, Pizzichini E, Sullivan SD, Wenzel SE, Zar HJ. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J. 2008 Jan; 31(1):143-78.
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81. Wang R, Lagakos SW, Ware JH, Hunter DJ, Drazen JM. Statistics in medicine--reporting of subgroup analyses in clinical trials. N Engl J Med. 2007 Nov 22; 357(21):2189-94.
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82. Drazen JM, Morrissey S, Curfman GD. Open clinical trials. N Engl J Med. 2007 Oct 25; 357(17):1756-7.
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83. Curfman GD, Morrissey S, Drazen JM. No child left uncovered. N Engl J Med. 2007 Sep 6; 357(10):1036-7.
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84. Curfman GD, Morrissey S, Drazen JM. Safer drugs for the American people. N Engl J Med. 2007 Aug 9; 357(6):602-3.
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85. [Clinical trial registration: looking back and moving ahead]. Ugeskr Laeger. 2007 Jun 25; 169(26):2505-6.
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86. Fredenburgh LE, Campion EW, Drazen JM. Clinical Decisions. Mild persistent asthma--polling results. N Engl J Med. 2007 Jul 12; 357(2):179-80.
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87. Laine C, Horton R, De Angelis C, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van Der Weyden MB, Verheugt FW. Clinical trial registration: looking back and moving ahead. Med J Aust. 2007 Jun 18; 186(12):612-3.
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88. Laine C, Horton R, DeAngelis C, Drazen J, Frizelle F, Godlee F, Haug C, Hébert P, Kotzin S, Marusic A, Sahni P, Schroeder T, Sox H, Van der Weyden M, Verheugt F. Clinical trial registration: looking back and moving ahead. N Z Med J. 2007; 120(1256):U2586.
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89. Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van der Weyden MB, Verheugt FW. Clinical trial registration: looking back and moving ahead. Lancet. 2007 Jun 9; 369(9577):1909-11.
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90. Drazen JM, Morrissey S, Curfman GD. Rosiglitazone--continued uncertainty about safety. N Engl J Med. 2007 Jul 5; 357(1):63-4.
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91. Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van der Weyden MB, Verheugt FW. Clinical trial registration. BMJ. 2007 Jun 9; 334(7605):1177-8.
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92. Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van der Weyden MB, Verheugt FW. Clinical trial registration: looking back and moving ahead. JAMA. 2007 Jul 4; 298(1):93-4.
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93. Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van der Weyden MB, Verheugt FW. Clinical trial registration: looking back and moving ahead. CMAJ. 2007 Jul 3; 177(1):57-8.
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94. Laine C, De Angelis C, Delamothe T, Drazen JM, Frizelle FA, Haug C, Hébert PC, Horton R, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van der Weyden MB, Verheugt FW. Clinical trial registration: looking back and moving ahead. Ann Intern Med. 2007 Aug 21; 147(4):275-7.
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95. Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van der Weyden MB, Verheugt FW. Clinical trial registration--looking back and moving ahead. N Engl J Med. 2007 Jun 28; 356(26):2734-6.
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96. Laine C, Horton R, DeAngelis CD, Drazen JM, Frizelle FA, Godlee F, Haug C, Hébert PC, Kotzin S, Marusic A, Sahni P, Schroeder TV, Sox HC, Van Der Weyden MB, Verheugt FW. Clinical trial registration: looking back and moving ahead. Croat Med J. 2007 Jun; 48(3):289-91.
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97. Baden LR, Curfman GD, Morrissey S, Drazen JM. Human papillomavirus vaccine--opportunity and challenge. N Engl J Med. 2007 May 10; 356(19):1990-1.
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98. Drazen JM. Government in medicine. N Engl J Med. 2007 May 24; 356(21):2195.
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99. Curfman GD, Morrissey S, Jarcho JA, Drazen JM. Drug-eluting coronary stents--promise and uncertainty. N Engl J Med. 2007 Mar 8; 356(10):1059-60.
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100. Drazen JM, Zarin DA. Salvation by registration. N Engl J Med. 2007 Jan 11; 356(2):184-5.
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101. Drazen JM. Research replication. N Engl J Med. 2006 Nov 23; 355(21):2252-3.
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102. Curfman GD, Morrissey S, Drazen JM. Retraction: Sudbø J et al. DNA content as a prognostic marker in patients with oral leukoplakia. N Engl J Med 2001;344:1270-8 and Sudbø J et al. The influence of resection and aneuploidy on mortality in oral leukoplakia. N Engl J Med 2004;350:1405-13. N Engl J Med. 2006 Nov 2; 355(18):1927.
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103. Curfman GD, Morrissey S, Drazen JM. Blueprint for a stronger Food and Drug Administration. N Engl J Med. 2006 Oct 26; 355(17):1821.
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104. Drazen JM. Response to 'Lapses at the NEJM'. J R Soc Med. 2006 Oct; 99(10):485; author reply 485.
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105. Chiang N, Serhan CN, Dahlén SE, Drazen JM, Hay DW, Rovati GE, Shimizu T, Yokomizo T, Brink C. The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo. Pharmacol Rev. 2006 Sep; 58(3):463-87.
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106. Drazen JM. Volunteers at risk. N Engl J Med. 2006 Sep 7; 355(10):1060-1.
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107. Drazen JM, Lenfant C, Hurd SS. Acorns and inhalers: the Asthma Clinical Research Network. J Allergy Clin Immunol. 2007 Jan; 119(1):28-9.
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108. Chu EK, Cheng J, Foley JS, Mecham BH, Owen CA, Haley KJ, Mariani TJ, Kohane IS, Tschumperlin DJ, Drazen JM. Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. Am J Respir Cell Mol Biol. 2006 Dec; 35(6):628-38.
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109. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Haematologica. 2006 Mar; 91(3):293-5.
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110. Curfman GD, Morrissey S, Drazen JM. Expression of concern reaffirmed. N Engl J Med. 2006 Mar 16; 354(11):1193.
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111. Curfman GD, Morrissey S, Drazen JM. Expression of concern: Sudbø J et al. DNA content as a prognostic marker in patients with oral leukoplakia. N Engl J Med 2001;344:1270-8 and Sudbø J et al. the influence of resection and aneuploidy on mortality in oral leukoplakia. N Engl J Med 2004;350:1405-13. N Engl J Med. 2006 Feb 9; 354(6):638.
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112. Tschumperlin DJ, Drazen JM. Chronic effects of mechanical force on airways. Annu Rev Physiol. 2006; 68:563-83.
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113. Drazen JM, Wood AJ. Trial registration report card. N Engl J Med. 2005 Dec 29; 353(26):2809-11.
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114. Curfman GD, Morrissey S, Drazen JM. Expression of concern: Bombardier et al., "Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis," N Engl J Med 2000;343:1520-8. N Engl J Med. 2005 Dec 29; 353(26):2813-4.
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115. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Saudi Med J. 2005 Dec; 26(12):1857-9.
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116. Wood AJ, Drazen JM, Greene MF. A sad day for science at the FDA. N Engl J Med. 2005 Sep 22; 353(12):1197-9.
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117. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the international committee of medical journal editors. Croat Med J. 2005 Aug; 46(4):499-501.
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118. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Ann Intern Med. 2005 Jul 19; 143(2):146-8.
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119. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. [Is this clinical trial fully registered?]. Tidsskr Nor Laegeforen. 2005 Jun 30; 125(13):1877-8.
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120. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Med J Aust. 2005 Jun 20; 182(12):609-10.
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121. Drazen JM. Patients at risk. N Engl J Med. 2005 Jul 28; 353(4):417.
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122. De Angelis C, Drazen J, Frizelle F, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke J, Schroeder T, Sox H, Van der Weyden M. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. N Z Med J. 2005 Jun 3; 118(1216):U1500.
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123. DeAngelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Arch Otolaryngol Head Neck Surg. 2005 Jun; 131(6):479-80.
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124. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered?--A statement from the International Committee of Medical Journal Editors. N Engl J Med. 2005 Jun 9; 352(23):2436-8.
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125. Deangelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. JAMA. 2005 Jun 15; 293(23):2927-9.
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126. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. CMAJ. 2005 Jun 21; 172(13):1700-2.
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127. Drazen JM. Using every resource to care for our casualties. N Engl J Med. 2005 May 19; 352(20):2121.
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128. Choudhry S, Avila PC, Nazario S, Ung N, Kho J, Rodriguez-Santana JR, Casal J, Tsai HJ, Torres A, Ziv E, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Castro RA, Selman M, Weiss ST, Ford JG, Drazen JM, Rodriguez-Cintron W, Chapela R, Silverman EK, Burchard EG. CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma. Am J Respir Crit Care Med. 2005 Jul 15; 172(2):173-82.
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129. De Angelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors. Lancet. 2005 May 28-Jun 3; 365(9474):1827-9.
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130. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Arterioscler Thromb Vasc Biol. 2005 Apr; 25(4):873-4.
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131. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Hypertension. 2005 Apr; 45(4):631-2.
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132. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Stroke. 2005 Apr; 36(4):924-5.
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133. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Circ Res. 2005 Mar 18; 96(5):600-1.
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134. Chu EK, Drazen JM. Asthma: one hundred years of treatment and onward. Am J Respir Crit Care Med. 2005 Jun 1; 171(11):1202-8.
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135. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Circulation. 2005 Mar 15; 111(10):1337-8.
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136. Drazen JM, Klempner MS. Disaster, water, cholera, vaccines, and hope. N Engl J Med. 2005 Feb 24; 352(8):827.
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137. Drazen JM. COX-2 inhibitors--a lesson in unexpected problems. N Engl J Med. 2005 Mar 17; 352(11):1131-2.
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138. Chu EK, Foley JS, Cheng J, Patel AS, Drazen JM, Tschumperlin DJ. Bronchial epithelial compression regulates epidermal growth factor receptor family ligand expression in an autocrine manner. Am J Respir Cell Mol Biol. 2005 May; 32(5):373-80.
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139. Ackerman KG, Huang H, Grasemann H, Puma C, Singer JB, Hill AE, Lander E, Nadeau JH, Churchill GA, Drazen JM, Beier DR. Interacting genetic loci cause airway hyperresponsiveness. Physiol Genomics. 2005 Mar 21; 21(1):105-11.
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140. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Am J Phys Med Rehabil. 2005 Jan; 84(1):3-4.
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141. Deangelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Arch Dermatol. 2005 Jan; 141(1):76-7.
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142. Drazen JM. Your health in the 21st century. Getting all the facts on drugs. Newsweek. 2005; 145(26A):72.
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143. Tantisira KG, Hwang ES, Raby BA, Silverman ES, Lake SL, Richter BG, Peng SL, Drazen JM, Glimcher LH, Weiss ST. TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18099-104.
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144. Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J, Torres A, Gorman JD, Salari K, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Castro RA, Salazar M, Gomez I, Fagan JK, Salas J, Clark S, Lilly C, Matallana H, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Drazen JM, Rodriguez-Cintron W, Silverman EK, Burchard EG. Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):563-70.
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145. Drazen JM. Awake and informed. N Engl J Med. 2004 Oct 28; 351(18):1884.
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146. Drazen JM. Embryonic stem-cell research--the case for federal funding. N Engl J Med. 2004 Oct 21; 351(17):1789-90.
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147. Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R, Craig TJ, Deykin A, Fagan JK, Fahy JV, Fish J, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Liggett SB, Martin RJ, Mitra N, Peters SP, Silverman E, Sorkness CA, Szefler SJ, Wechsler ME, Weiss ST, Drazen JM. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet. 2004 Oct 23-29; 364(9444):1505-12.
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148. Drazen JM. Presentation of the 2004 Kober Medal to K. Frank Austen. J Clin Invest. 2004 Oct; 114(8):1174-6.
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149. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Croat Med J. 2004 Oct; 45(5):531-2.
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150. Drazen JM, Curfman GD. Public access to biomedical research. N Engl J Med. 2004 Sep 23; 351(13):1343.
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151. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. [Clinical trial registration: a statement from the International Committee of Medical Journal Editors]. Tidsskr Nor Laegeforen. 2004 Sep 23; 124(18):2339.
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152. DeAngelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Med J Aust. 2004 Sep 20; 181(6):293-4.
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153. DeAngelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, van der Weyden MB. [Registration of clinical trials: a statement from the International Committee of Medical Journal Editors]. Ned Tijdschr Geneeskd. 2004 Sep 18; 148(38):1870-1.
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154. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. CMAJ. 2004 Sep 14; 171(6):606-7.
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155. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. [Clinical trial registration: a statement for the International Committee of Medical Journal Editors]. Ugeskr Laeger. 2004 Sep 13; 166(38):3283-4.
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156. Drazen JM. Editorial independence at the BMJ: NEJM editor says facts in letter are wrong and accusations reckless... BMJ. 2004 Sep 11; 329(7466):624.
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157. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. N Z Med J. 2004 Sep 10; 117(1201):U1054.
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158. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Ann Intern Med. 2004 Sep 21; 141(6):477-8.
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159. DeAngelis CD, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. JAMA. 2004 Sep 15; 292(11):1363-4.
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160. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. N Engl J Med. 2004 Sep 16; 351(12):1250-1.
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161. De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Lancet. 2004 Sep 11-17; 364(9438):911-2.
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162. Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, Eidelman D, Ludwig M, Macklem P, Martin J, Milic-Emili J, Hantos Z, Hyatt R, Lai-Fook S, Leff A, Solway J, Lutchen K, Suki B, Mitzner W, Paré P, Pride N, Sly P. The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol. 2004 Sep; 31(3):373-4.
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163. Tantisira KG, Lake S, Silverman ES, Palmer LJ, Lazarus R, Silverman EK, Liggett SB, Gelfand EW, Rosenwasser LJ, Richter B, Israel E, Wechsler M, Gabriel S, Altshuler D, Lander E, Drazen J, Weiss ST. Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum Mol Genet. 2004 Jul 1; 13(13):1353-9.
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164. Tschumperlin DJ, Dai G, Maly IV, Kikuchi T, Laiho LH, McVittie AK, Haley KJ, Lilly CM, So PT, Lauffenburger DA, Kamm RD, Drazen JM. Mechanotransduction through growth-factor shedding into the extracellular space. Nature. 2004 May 6; 429(6987):83-6.
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165. Drazen JM, Greene MF, Wood AJ. The FDA, politics, and plan B. N Engl J Med. 2004 Apr 8; 350(15):1561-2.
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166. Ingelfinger JR, Drazen JM. Registry research and medical privacy. N Engl J Med. 2004 Apr 1; 350(14):1452-3.
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167. Kikuchi T, Shively JD, Foley JS, Drazen JM, Tschumperlin DJ. Differentiation-dependent responsiveness of bronchial epithelial cells to IL-4/13 stimulation. Am J Physiol Lung Cell Mol Physiol. 2004 Jul; 287(1):L119-26.
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168. Hjoberg J, Shore S, Kobzik L, Okinaga S, Hallock A, Vallone J, Subramaniam V, De Sanctis GT, Elias JA, Drazen JM, Silverman ES. Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness. J Appl Physiol. 2004 Jul; 97(1):249-59.
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169. Phimister EG, Drazen JM. Two fillips for human embryonic stem cells. N Engl J Med. 2004 Mar 25; 350(13):1351-2.
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170. Brink C, Dahlén SE, Drazen J, Evans JF, Hay DW, Rovati GE, Serhan CN, Shimizu T, Yokomizo T. International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor. Pharmacol Rev. 2004 Mar; 56(1):149-57.
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171. Drazen JM. Inserting government between patient and physician. N Engl J Med. 2004 Jan 8; 350(2):178-9.
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172. Weiss ST, Lake SL, Silverman ES, Silverman EK, Richter B, Drazen JM, Tantisira KG. Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses. Proc Am Thorac Soc. 2004; 1(4):364-7.
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173. Drazen JM, Ingelfinger JR. Grants, politics, and the NIH. N Engl J Med. 2003 Dec 4; 349(23):2259-61.
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174. Burchard EG, Avila PC, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Ziv E, Castro R, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Rodriguez-Cintron W, Drazen JM, Silverman EK. Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med. 2004 Feb 1; 169(3):386-92.
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175. Drazen JM, Ingelfinger JR, Curfman GD. Removal of expression of concern: Schiffl H, et Al. Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 2002;346:305-10. N Engl J Med. 2003 Nov 13; 349(20):1965.
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176. Silverman EK, Kwiatkowski DJ, Sylvia JS, Lazarus R, Drazen JM, Lange C, Laird NM, Weiss ST. Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol. 2003 Nov; 112(5):870-6.
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177. Thompson MD, Storm van's Gravesande K, Galczenski H, Burnham WM, Siminovitch KA, Zamel N, Slutsky A, Drazen JM, George SR, Evans JF, O'Dowd BF. A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha. Pharmacogenetics. 2003 Oct; 13(10):641-9.
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178. Drazen JM. Decisions at the end of life. N Engl J Med. 2003 Sep 18; 349(12):1109-10.
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179. Shore SA, Drazen JM. Beta-agonists and asthma: too much of a good thing? J Clin Invest. 2003 Aug; 112(4):495-7.
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180. Drazen JM. SARS--looking back over the first 100 days. N Engl J Med. 2003 Jul 24; 349(4):319-20.
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181. Drazen JM. Legislative myopia on stem cells. N Engl J Med. 2003 Jul 17; 349(3):300.
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182. Silverman ES, Drazen JM. Immunostimulatory DNA for asthma: better than eating dirt. Am J Respir Cell Mol Biol. 2003 Jun; 28(6):645-7.
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183. Curfman GD, Morrissey S, Drazen JM. Notice of duplicate publication. N Engl J Med. 2003 May 29; 348(22):2254.
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184. Drazen JM, Ingelfinger JR, Curfman GD. Expression of concern: Schiffl H, et Al. Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 2002;346:305-10. N Engl J Med. 2003 May 22; 348(21):2137.
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185. Drazen JM, Epstein AM. Guidance concerning surgery for emphysema. N Engl J Med. 2003 May 22; 348(21):2134-6.
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186. Drazen JM, Campion EW. SARS, the Internet, and the Journal. N Engl J Med. 2003 May 15; 348(20):2029.
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187. Storm van's Gravesande K, Wechsler ME, Grasemann H, Silverman ES, Le L, Palmer LJ, Drazen JM. Association of a missense mutation in the NOS3 gene with exhaled nitric oxide levels. Am J Respir Crit Care Med. 2003 Jul 15; 168(2):228-31.
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188. Drazen JM. Controlling research trials. N Engl J Med. 2003 Apr 3; 348(14):1377-80.
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189. Drazen JM. Case clusters of the severe acute respiratory syndrome. N Engl J Med. 2003 May 15; 348(20):e6-7.
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190. Brink C, Dahlén SE, Drazen J, Evans JF, Hay DW, Nicosia S, Serhan CN, Shimizu T, Yokomizo T. International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol Rev. 2003 Mar; 55(1):195-227.
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191. Drazen JM. Asthma and the human genome project: summary of the 45th Annual Thomas L. Petty Aspen Lung Conference. Chest. 2003 Mar; 123(3 Suppl):447S-9S.
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192. Drazen JM. Inappropriate advertising of dietary supplements. N Engl J Med. 2003 Feb 27; 348(9):777-8.
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193. Curfman GD, Morrissey S, Drazen JM. Notice of retraction. N Engl J Med. 2003 Mar 6; 348(10):945.
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194. Tschumperlin DJ, Shively JD, Kikuchi T, Drazen JM. Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium. Am J Respir Cell Mol Biol. 2003 Feb; 28(2):142-9.
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195. Grasemann H, Storm van's Gravesande K, Buscher R, Drazen JM, Ratjen F. Effects of sex and of gene variants in constitutive nitric oxide synthases on exhaled nitric oxide. Am J Respir Crit Care Med. 2003 Apr 15; 167(8):1113-6.
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196. Drazen JM. Leukotrienes in asthma. Adv Exp Med Biol. 2003; 525:1-5.
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197. Kalayci O, Wechsler M, Galper B, Hong C, Israel E, Drazen JM, Lilly CM. LTC4 production by eosinophils in asthmatic subjects with alternative forms of ALOX-5 core promoter. Adv Exp Med Biol. 2003; 525:11-4.
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198. Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt B, Szczeklik W, Drazen JM, Serhan CN. Lipoxins and aspirin-triggered lipoxins in airway responses. Adv Exp Med Biol. 2003; 525:19-23.
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199. Silverman ES, Baron RM, Palmer LJ, Le L, Hallock A, Subramaniam V, Riese RJ, McKenna MD, Gu X, Libermann TA, Tugores A, Haley KJ, Shore S, Drazen JM, Weiss ST. Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung. Am J Respir Cell Mol Biol. 2002 Dec; 27(6):697-704.
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200. DeMeo DL, Lange C, Silverman EK, Senter JM, Drazen JM, Barth MJ, Laird N, Weiss ST. Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genet Epidemiol. 2002 Nov; 23(4):335-48.
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201. Drazen JM. A milestone in tuberculosis control. N Engl J Med. 2002 Oct 31; 347(18):1444.
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202. Mushlin SB, Drazen JM, Samuels MA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2002. A 28-year-old woman with ocular inflammation, fever, and headache. N Engl J Med. 2002 Oct 24; 347(17):1350-7.
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203. Drazen JM. Institutions, contracts, and academic freedom. N Engl J Med. 2002 Oct 24; 347(17):1362-3.
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204. Drazen JM, Epstein AM. Rethinking medical training--the critical work ahead. N Engl J Med. 2002 Oct 17; 347(16):1271-2.
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205. Baron RM, Palmer LJ, Tantisira K, Gabriel S, Sonna LA, Le L, Hallock A, Libermann TA, Drazen JM, Weiss ST, Silverman ES. DNA sequence variants in epithelium-specific ETS-2 and ETS-3 are not associated with asthma. Am J Respir Crit Care Med. 2002 Oct 1; 166(7):927-32.
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206. Hare JM, Nguyen GC, Massaro AF, Drazen JM, Stevenson LW, Colucci WS, Fang JC, Johnson W, Givertz MM, Lucas C. Exhaled nitric oxide: a marker of pulmonary hemodynamics in heart failure. J Am Coll Cardiol. 2002 Sep 18; 40(6):1114-9.
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207. Slutsky AS, Drazen JM. Ventilation with small tidal volumes. N Engl J Med. 2002 Aug 29; 347(9):630-1.
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208. Grasemann H, Storm van's Gravesande K, Buscher R, Knauer N, Silverman ES, Palmer LJ, Drazen JM, Ratjen F. Endothelial nitric oxide synthase variants in cystic fibrosis lung disease. Am J Respir Crit Care Med. 2003 Feb 1; 167(3):390-4.
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209. Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt BA, Szczeklik W, Drazen JM, Serhan CN. Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4). Nat Med. 2002 Sep; 8(9):1018-23.
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210. Hrousis CA, Wiggs BJ, Drazen JM, Parks DM, Kamm RD. Mucosal folding in biologic vessels. J Biomech Eng. 2002 Aug; 124(4):334-41.
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211. Drazen JM, Weiss ST. Genetics: inherit the wheeze. Nature. 2002 Jul 25; 418(6896):383-4.
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212. Drazen JM, Curfman GD. Retraction: Barbaro et Al. Incidence of dilated cardiomyopathy and detection of HIV in myocardial cells of HIV-positive patients. N Engl J Med 1998;339:1093-9. N Engl J Med. 2002 Jul 11; 347(2):140.
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213. Drazen JM, Curfman GD. On authors and contributors. N Engl J Med. 2002 Jul 4; 347(1):55.
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214. Drazen JM. Who owns the data in clinical trial? Sci Eng Ethics. 2002 Jul; 8(3):407-11.
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215. Shikanai T, Silverman ES, Morse BW, Lilly CM, Inoue H, Drazen JM. Sequence variants in the FcepsilonRI alpha chain gene. J Appl Physiol. 2002 Jul; 93(1):37-41.
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216. Deykin A, Massaro AF, Drazen JM, Israel E. Exhaled nitric oxide as a diagnostic test for asthma: online versus offline techniques and effect of flow rate. Am J Respir Crit Care Med. 2002 Jun 15; 165(12):1597-601.
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217. Drazen JM, Curfman GD. Financial associations of authors. N Engl J Med. 2002 Jun 13; 346(24):1901-2.
  View in: PubMed
 
218. Martin RJ, Szefler SJ, Chinchilli VM, Kraft M, Dolovich M, Boushey HA, Cherniack RM, Craig TJ, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kunselman SJ, Lazarus SC, Lemanske RF, Peters SP, Sorkness CA. Systemic effect comparisons of six inhaled corticosteroid preparations. Am J Respir Crit Care Med. 2002 May 15; 165(10):1377-83.
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219. Tschumperlin DJ, Shively JD, Swartz MA, Silverman ES, Haley KJ, Raab G, Drazen JM. Bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression. Am J Physiol Lung Cell Mol Physiol. 2002 May; 282(5):L904-11.
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220. Palmer LJ, Silverman ES, Weiss ST, Drazen JM. Pharmacogenetics of asthma. Am J Respir Crit Care Med. 2002 Apr 1; 165(7):861-6.
  View in: PubMed
 
221. Drazen JM. Smallpox and bioterrorism. N Engl J Med. 2002 Apr 25; 346(17):1262-3.
  View in: PubMed
 
222. Silverman EK, Palmer LJ, Mosley JD, Barth M, Senter JM, Brown A, Drazen JM, Kwiatkowski DJ, Chapman HA, Campbell EJ, Province MA, Rao DC, Reilly JJ, Ginns LC, Speizer FE, Weiss ST. Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet. 2002 May; 70(5):1229-39.
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223. Silverman EK, Mosley JD, Palmer LJ, Barth M, Senter JM, Brown A, Drazen JM, Kwiatkowski DJ, Chapman HA, Campbell EJ, Province MA, Rao DC, Reilly JJ, Ginns LC, Speizer FE, Weiss ST. Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes. Hum Mol Genet. 2002 Mar 15; 11(6):623-32.
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224. Grasemann H, Storm van's Gravesande K, Gärtig S, Kirsch M, Büscher R, Drazen JM, Ratjen F. Nasal nitric oxide levels in cystic fibrosis patients are associated with a neuronal NO synthase (NOS1) gene polymorphism. Nitric Oxide. 2002 Mar; 6(2):236-41.
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225. Szefler SJ, Martin RJ, King TS, Boushey HA, Cherniack RM, Chinchilli VM, Craig TJ, Dolovich M, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lazarus SC, Lemanske RF, Mauger E, Peters SP, Sorkness CA. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol. 2002 Mar; 109(3):410-8.
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226. Drazen JM. The consumer and the learned intermediary in health care. N Engl J Med. 2002 Feb 14; 346(7):523-4.
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227. Drazen JM. Sleep apnea syndrome. N Engl J Med. 2002 Feb 7; 346(6):390.
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228. Oguma T, Asano K, Shiomi T, Fukunaga K, Suzuki Y, Nakamura M, Matsubara H, Sheldon HK, Haley KJ, Lilly CM, Drazen JM, Yamaguchi K. Cyclooxygenase-2 expression during allergic inflammation in guinea-pig lungs. Am J Respir Crit Care Med. 2002 Feb 1; 165(3):382-6.
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229. Campion EW, Anderson K, Drazen JM. Advances in our electronic pages. N Engl J Med. 2002 Jan 31; 346(5):362.
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230. Drazen JM. Allocating limited resources. N Engl J Med. 2002 Jan 31; 346(5):368.
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231. Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science. 2002 Jan 11; 295(5553):336-8.
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232. Drazen JM. Anti-leukotrienes as novel anti-inflammatory treatments in asthma. Adv Exp Med Biol. 2002; 507:217-21.
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233. Nakamura H, Luster AD, Nakamura T, In KH, Sonna LA, Deykin A, Israel E, Drazen JM, Lilly CM. Variant eotaxin: its effects on the asthma phenotype. J Allergy Clin Immunol. 2001 Dec; 108(6):946-53.
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234. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Højgaard L, Horton R, Kotzin S, Nicholls MG, Nylenna M, Overbeke AJ, Sox HC, Van der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. Obstet Gynecol. 2001 Dec; 98(6):1143-6.
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235. Chinchilli VM, Drazen JM, Fish JE, Lemanske RF, Lazarus SC, Martin RJ. The clinical trials in the initial five-year award period of the Asthma Clinical Research Network. Control Clin Trials. 2001 Dec; 22(6 Suppl):126S-34S.
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236. Forand PE, Kunselman SJ, Drazen JM, Israel E, Pillari A, Armstrong TJ, Britton TB. Genetic analysis in the Asthma Clinical Research Network. Control Clin Trials. 2001 Dec; 22(6 Suppl):196S-206S.
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237. Tschumperlin DJ, Drazen JM. Mechanical stimuli to airway remodeling. Am J Respir Crit Care Med. 2001 Nov 15; 164(10 Pt 2):S90-4.
  View in: PubMed
 
238. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Hjgaard L, Horton R, Kotzin S, Nicholls MG, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. [Sponsorship, authorship and accountability]. Rev Esp Cardiol. 2001 Nov; 54(11):1247-50.
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239. Barr RG, Cooper DM, Speizer FE, Drazen JM, Camargo CA. Beta(2)-adrenoceptor polymorphism and body mass index are associated with adult-onset asthma in sedentary but not active women. Chest. 2001 Nov; 120(5):1474-9.
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240. Davidoff F, DeAngelis CD, Drazen JM, Nicholls MG, Hoey J, Højgaard L, Horton R, Kotzin S, Nylenna M, Overbeke JP, Sox HC, Van der Weyden MB, Wilkes MS. Sponsorship, authorship and accountability. Lakartidningen. 2001 Oct 24; 98(43):4694-6.
  View in: PubMed
 
241. Drazen JM. Surgery for emphysema--not for everyone. N Engl J Med. 2001 Oct 11; 345(15):1126-7.
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242. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Højgaard L, Horton R, Kotzin S, Nicholls MG, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. Arch Otolaryngol Head Neck Surg. 2001 Oct; 127(10):1178-80.
  View in: PubMed
 
243. Baron R, Silverman ES, Grasemann H, Collins T, Drazen JM. DNA sequence variants of the platelet-derived growth factor A-chain gene. Clin Exp Allergy. 2001 Oct; 31(10):1501-8.
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244. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Højgaard L, Horton R, Kotzin S, Nylenna M, Overbeke AJ, Sox HC, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. Ann Intern Med. 2001 Sep 18; 135(6):463-6.
  View in: PubMed
 
245. Davidoff F, DeAngelis CD, Drazen JM, Nicholls MG, Hoey J, Højgaard L, Horton R, Kotzin S, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship and accountability. CMAJ. 2001 Sep 18; 165(6):786-8.
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246. Davidoff F, DeAngelis CD, Drazen JM, Nicholls MG, Hoey J, Højgaard L, Horton R, Kotzin S, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship and accountability. Med J Aust. 2001 Sep 17; 175(6):294-6.
  View in: PubMed
 
247. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Højgaard L, Horton R, Kotzin S, Nicholls MG, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. Lancet. 2001 Sep 15; 358(9285):854-6.
  View in: PubMed
 
248. Davidoff F, DeAngelis CD, Drazen JM, Nicholls MG, Hoey J, Højgaard L, Horton R, Kotzin S, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. N Engl J Med. 2001 Sep 13; 345(11):825-6; discussion 826-7.
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249. Curfman GD, Drazen JM. Too close to call. N Engl J Med. 2001 Sep 13; 345(11):832.
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250. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Højgaard L, Horton R, Kotzin S, Nicholls MG, Nylenna M, Overbeke AJ, Sox HC, Van Der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. JAMA. 2001 Sep 12; 286(10):1232-4.
  View in: PubMed
 
251. Davidoff F, Deangelis CD, Drazen JM, Nicholls MG, Hoey J, Hojgaard L, Horton R, Kotzin S, Nylenna M, Overbeke JP, Sox HC, Van der Weyden MB, Wilkes MS. Sponsorship, authorship, and accountability. Ugeskr Laeger. 2001 Sep 10; 163(37):4983-5.
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252. Davidoff F, DeAngelis CD, Drazen JM, Hoey J, Højgaard L, Horton R, Kotzin S, Nicholls MG, Nylenna M, Overbeke JP, Sox HC, van der Weyden MB, Wilkes MS. [Sponsorship, authorship and accountability]. Tidsskr Nor Laegeforen. 2001 Sep 10; 121(21):2531-2.
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253. Steinbrook R, Drazen JM. AIDS--will the next 20 years be different? N Engl J Med. 2001 Jun 7; 344(23):1781-2.
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254. Yu H, Merchant B, Scheffel C, Yandava C, Drazen JM, Huff J. Automated detection of single nucleotide polymorphism in beta-2 adrenergic receptor gene using LCx(R). Clin Chim Acta. 2001 Jun; 308(1-2):17-24.
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255. Swartz MA, Tschumperlin DJ, Kamm RD, Drazen JM. Mechanical stress is communicated between different cell types to elicit matrix remodeling. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6180-5.
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256. Huang C, De Sanctis GT, O'Brien PJ, Mizgerd JP, Friend DS, Drazen JM, Brass LF, Stevens RL. Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung. J Biol Chem. 2001 Jul 13; 276(28):26276-84.
  View in: PubMed
 
257. Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Lemanske RF, Sorkness CA, Kraft M, Fish JE, Peters SP, Craig T, Drazen JM, Ford JG, Israel E, Martin RJ, Mauger EA, Nachman SA, Spahn JD, Szefler SJ. Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial. JAMA. 2001 May 23-30; 285(20):2583-93.
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258. Lemanske RF, Sorkness CA, Mauger EA, Lazarus SC, Boushey HA, Fahy JV, Drazen JM, Chinchilli VM, Craig T, Fish JE, Ford JG, Israel E, Kraft M, Martin RJ, Nachman SA, Peters SP, Spahn JD, Szefler SJ. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. JAMA. 2001 May 23-30; 285(20):2594-603.
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259. Wang Z, Chen C, Niu T, Wu D, Yang J, Wang B, Fang Z, Yandava CN, Drazen JM, Weiss ST, Xu X. Association of asthma with beta(2)-adrenergic receptor gene polymorphism and cigarette smoking. Am J Respir Crit Care Med. 2001 May; 163(6):1404-9.
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260. Fahy JV, Boushey HA, Lazarus SC, Mauger EA, Cherniack RM, Chinchilli VM, Craig TJ, Drazen JM, Ford JG, Fish JE, Israel E, Kraft M, Lemanske RF, Martin RJ, McLean D, Peters SP, Sorkness C, Szefler SJ. Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med. 2001 May; 163(6):1470-5.
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261. Leone FT, Mauger EA, Peters SP, Chinchilli VM, Fish JE, Boushey HA, Cherniack RM, Drazen JM, Fahy JV, Ford J, Israel E, Lazarus SC, Lemanske RF, Martin RJ, McGeady SJ, Sorkness C, Szefler SJ. The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research. Chest. 2001 Apr; 119(4):1027-33.
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262. Antman K, Lagakos S, Drazen J. Designing and funding clinical trials of novel therapies. N Engl J Med. 2001 Mar 8; 344(10):762-3.
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263. Silverman ES, De Sanctis GT, Boyce J, Maclean JA, Jiao A, Green FH, Grasemann H, Faunce D, Fitzmaurice G, Shi GP, Stein-Streilein J, Milbrandt J, Collins T, Drazen JM. The transcription factor early growth-response factor 1 modulates tumor necrosis factor-alpha, immunoglobulin E, and airway responsiveness in mice. Am J Respir Crit Care Med. 2001 Mar; 163(3 Pt 1):778-85.
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264. Moy ML, Israel E, Weiss ST, Juniper EF, Dubé L, Drazen JM. Clinical predictors of health-related quality of life depend on asthma severity. Am J Respir Crit Care Med. 2001 Mar; 163(4):924-9.
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265. Epstein AM, Drazen JM, Steinbrook R. Health policy 2001--a new series. N Engl J Med. 2001 Mar 1; 344(9):673.
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266. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, Cooper DM, Fahy JV, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Martin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN. Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int Arch Allergy Immunol. 2001 Jan-Mar; 124(1-3):183-6.
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267. Silverman ES, Liggett SB, Gelfand EW, Rosenwasser LJ, Baron RM, Bolk S, Weiss ST, Drazen JM. The pharmacogenetics of asthma: a candidate gene approach. Pharmacogenomics J. 2001; 1(1):27-37.
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268. MacLean JA, De Sanctis GT, Ackerman KG, Drazen JM, Sauty A, DeHaan E, Green FH, Charo IF, Luster AD. CC chemokine receptor-2 is not essential for the development of antigen-induced pulmonary eosinophilia and airway hyperresponsiveness. J Immunol. 2000 Dec 1; 165(11):6568-75.
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269. Wechsler ME, Grasemann H, Deykin A, Silverman EK, Yandava CN, Israel E, Wand M, Drazen JM. Exhaled nitric oxide in patients with asthma: association with NOS1 genotype. Am J Respir Crit Care Med. 2000 Dec; 162(6):2043-7.
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270. Moore PE, Laporte JD, Abraham JH, Schwartzman IN, Yandava CN, Silverman ES, Drazen JM, Wand MP, Panettieri RA, Shore SA. Polymorphism of the beta(2)-adrenergic receptor gene and desensitization in human airway smooth muscle. Am J Respir Crit Care Med. 2000 Dec; 162(6):2117-24.
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271. Silverman EK, Weiss ST, Drazen JM, Chapman HA, Carey V, Campbell EJ, Denish P, Silverman RA, Celedon JC, Reilly JJ, Ginns LC, Speizer FE. Gender-related differences in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2000 Dec; 162(6):2152-8.
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272. Grasemann H, Knauer N, BĂĽscher R, HĂĽbner K, Drazen JM, Ratjen F. Airway nitric oxide levels in cystic fibrosis patients are related to a polymorphism in the neuronal nitric oxide synthase gene. Am J Respir Crit Care Med. 2000 Dec; 162(6):2172-6.
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273. Drazen JM, Koski G. To protect those who serve. N Engl J Med. 2000 Nov 30; 343(22):1643-5.
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274. Campion EW, Curfman GD, Drazen JM. Tracking the peer-review process. N Engl J Med. 2000 Nov 16; 343(20):1485-6.
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275. Drazen JM, Bush GW, Gore A. The Republican and Democratic candidates speak on health care. N Engl J Med. 2000 Oct 19; 343(16):1184-9.
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276. Taylor DR, Drazen JM, Herbison GP, Yandava CN, Hancox RJ, Town GI. Asthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphism. Thorax. 2000 Sep; 55(9):762-7.
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277. Harel Z, Lilly C, Riggs S, Vaz R, Drazen J. Urinary leukotriene (LT) E(4) in adolescents with dysmenorrhea: a pilot study. J Adolesc Health. 2000 Sep; 27(3):151-4.
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278. Drazen JM. Looking forward to serving you every week. N Engl J Med. 2000 Jul 6; 343(1):57-8.
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279. Van Sambeek R, Stevenson DD, Baldasaro M, Lam BK, Zhao J, Yoshida S, Yandora C, Drazen JM, Penrose JF. 5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. J Allergy Clin Immunol. 2000 Jul; 106(1 Pt 1):72-6.
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280. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, Cooper DM, Fahy JV, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Martin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN. The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med. 2000 Jul; 162(1):75-80.
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281. Grasemann H, Yandava CN, Storm van's Gravesande K, Deykin A, Pillari A, Ma J, Sonna LA, Lilly C, Stampfer MJ, Israel E, Silverman EK, Drazen JM. A neuronal NO synthase (NOS1) gene polymorphism is associated with asthma. Biochem Biophys Res Commun. 2000 Jun 7; 272(2):391-4.
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282. Ressler B, Lee RT, Randell SH, Drazen JM, Kamm RD. Molecular responses of rat tracheal epithelial cells to transmembrane pressure. Am J Physiol Lung Cell Mol Physiol. 2000 Jun; 278(6):L1264-72.
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283. Dellaripa PF, Wechsler ME, Roth ME, Drazen J. Recurrent panniculitis in a man with asthma receiving treatment with leukotriene-modifying agents. Mayo Clin Proc. 2000 Jun; 75(6):643-5.
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284. Deykin A, Massaro AF, Coulston E, Drazen JM, Israel E. Exhaled nitric oxide following repeated spirometry or repeated plethysmography in healthy individuals. Am J Respir Crit Care Med. 2000 Apr; 161(4 Pt 1):1237-40.
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285. Wechsler ME, Finn D, Gunawardena D, Westlake R, Barker A, Haranath SP, Pauwels RA, Kips JC, Drazen JM. Churg-Strauss syndrome in patients receiving montelukast as treatment for asthma. Chest. 2000 Mar; 117(3):708-13.
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286. Silverman ES, Drazen JM. Genetic variations in the 5-lipoxygenase core promoter. Description and functional implications. Am J Respir Crit Care Med. 2000 Feb; 161(2 Pt 2):S77-80.
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287. Drazen JM, Silverman EK, Lee TH. Heterogeneity of therapeutic responses in asthma. Br Med Bull. 2000; 56(4):1054-70.
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288. Nakamura H, Weiss ST, Israel E, Luster AD, Drazen JM, Lilly CM. Eotaxin and impaired lung function in asthma. Am J Respir Crit Care Med. 1999 Dec; 160(6):1952-6.
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289. De Sanctis GT, Singer JB, Jiao A, Yandava CN, Lee YH, Haynes TC, Lander ES, Beier DR, Drazen JM. Quantitative trait locus mapping of airway responsiveness to chromosomes 6 and 7 in inbred mice. Am J Physiol. 1999 Dec; 277(6 Pt 1):L1118-23.
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290. Grasemann H, Yandava CN, Drazen JM. Neuronal NO synthase (NOS1) is a major candidate gene for asthma. Clin Exp Allergy. 1999 Dec; 29 Suppl 4:39-41.
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291. Silverman ES, Drazen JM. The biology of 5-lipoxygenase: function, structure, and regulatory mechanisms. Proc Assoc Am Physicians. 1999 Nov-Dec; 111(6):525-36.
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292. Drazen JM. Asthma therapy with agents preventing leukotriene synthesis or action. Proc Assoc Am Physicians. 1999 Nov-Dec; 111(6):547-59.
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293. Celedon JC, Speizer FE, Drazen JM, Weiss ST, Campbell EJ, Carey VJ, Reilly JJ, Ginns L, Silverman EK. Bronchodilator responsiveness and serum total IgE levels in families of probands with severe early-onset COPD. Eur Respir J. 1999 Nov; 14(5):1009-14.
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294. Yandava CN, Pillari A, Drazen JM. Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively. Genomics. 1999 Oct 1; 61(1):108-11.
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295. Wechsler ME, Pauwels R, Drazen JM. Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal? Drug Saf. 1999 Oct; 21(4):241-51.
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296. Lilly CM, Woodruff PG, Camargo CA, Nakamura H, Drazen JM, Nadel ES, Hanrahan JP. Elevated plasma eotaxin levels in patients with acute asthma. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 1):786-90.
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297. Burchard EG, Silverman EK, Rosenwasser LJ, Borish L, Yandava C, Pillari A, Weiss ST, Hasday J, Lilly CM, Ford JG, Drazen JM. Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma. Am J Respir Crit Care Med. 1999 Sep; 160(3):919-22.
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298. Wechsler ME, Drazen JM. Zafirlukast and Churg-Strauss syndrome. Chest. 1999 Jul; 116(1):266-7.
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299. Wechsler M, Drazen JM. Churg-Strauss syndrome. Lancet. 1999 Jun 5; 353(9168):1970-1.
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300. Drazen JM, Takebayashi T, Long NC, De Sanctis GT, Shore SA. Animal models of asthma and chronic bronchitis. Clin Exp Allergy. 1999 Jun; 29 Suppl 2:37-47.
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301. Grasemann H, Drazen JM, Deykin A, Israel E, De Sanctis GT, Pillari A, Yandava CH. Simple tandem repeat polymorphisms in the neuronal nitric oxide synthase gene in different ethnic populations. Hum Hered. 1999 Jun; 49(3):139-41.
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302. Drazen JM, Yandava CN, Dubé L, Szczerback N, Hippensteel R, Pillari A, Israel E, Schork N, Silverman ES, Katz DA, Drajesk J. Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat Genet. 1999 Jun; 22(2):168-70.
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303. De Sanctis GT, MacLean JA, Hamada K, Mehta S, Scott JA, Jiao A, Yandava CN, Kobzik L, Wolyniec WW, Fabian AJ, Venugopal CS, Grasemann H, Huang PL, Drazen JM. Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. J Exp Med. 1999 May 17; 189(10):1621-30.
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304. In KH, Silverman ES, Asano K, Beier D, Fischer AR, Keith TP, Serino K, Yandava C, De Sanctis GT, Drazen JM. Mutations in the human 5-lipoxygenase gene. Clin Rev Allergy Immunol. 1999 Spring-Summer; 17(1-2):59-69.
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305. MacLean JA, Sauty A, Luster AD, Drazen JM, De Sanctis GT. Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice. Am J Respir Cell Mol Biol. 1999 Mar; 20(3):379-87.
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306. Yandava CN, Kennedy BP, Pillari A, Duncan AM, Drazen JM. Cytogenetic and radiation hybrid mapping of human arachidonate 5-lipoxygenase-activating protein (ALOX5AP) to chromosome 13q12. Genomics. 1999 Feb 15; 56(1):131-3.
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307. De Sanctis GT, MacLean JA, Qin S, Wolyniec WW, Grasemann H, Yandava CN, Jiao A, Noonan T, Stein-Streilein J, Green FH, Drazen JM. Interleukin-8 receptor modulates IgE production and B-cell expansion and trafficking in allergen-induced pulmonary inflammation. J Clin Invest. 1999 Feb; 103(4):507-15.
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308. Drazen JM, Silverman ES. Genetic determinants of 5-lipoxygenase transcription. Int Arch Allergy Immunol. 1999 Feb-Apr; 118(2-4):275-8.
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309. Drazen JM, Israel E, O'Byrne PM. Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med. 1999 Jan 21; 340(3):197-206.
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310. Noviski N, Brewer JP, Skornik WA, Galli SJ, Drazen JM, Martin TR. Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice. J Appl Physiol. 1999 Jan; 86(1):202-10.
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311. Drazen JM, Finn PW, De Sanctis GT. Mouse models of airway responsiveness: physiological basis of observed outcomes and analysis of selected examples using these outcome indicators. Annu Rev Physiol. 1999; 61:593-625.
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312. Drazen JM, Israel E. Should antileukotriene therapies be used instead of inhaled corticosteroids in asthma? Yes. Am J Respir Crit Care Med. 1998 Dec; 158(6):1697-8.
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313. Silverman ES, Du J, Williams AJ, Wadgaonkar R, Drazen JM, Collins T. cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem J. 1998 Nov 15; 336 ( Pt 1):183-9.
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314. Mehta S, Boudreau J, Lilly CM, Drazen JM. Endogenous pulmonary nitric oxide in the regulation of airway microvascular leak. Am J Physiol. 1998 Nov; 275(5 Pt 1):L961-8.
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315. Drazen JM. Leukotrienes as mediators of airway obstruction. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 3):S193-200.
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316. Silverman E, In KH, Yandava C, Drazen JM. Pharmacogenetics of the 5-lipoxygenase pathway in asthma. Clin Exp Allergy. 1998 Nov; 28 Suppl 5:164-70; discussion 171-3.
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317. Silverman ES, Du J, De Sanctis GT, RĂĄdmark O, Samuelsson B, Drazen JM, Collins T. Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. Am J Respir Cell Mol Biol. 1998 Aug; 19(2):316-23.
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318. Haley KJ, Sunday ME, Wiggs BR, Kozakewich HP, Reilly JJ, Mentzer SJ, Sugarbaker DJ, Doerschuk CM, Drazen JM. Inflammatory cell distribution within and along asthmatic airways. Am J Respir Crit Care Med. 1998 Aug; 158(2):565-72.
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319. Ruddy MK, Drazen JM, Pitkanen OM, Rafii B, O'Brodovich HM, Harris HW. Modulation of aquaporin 4 and the amiloride-inhibitable sodium channel in perinatal rat lung epithelial cells. Am J Physiol. 1998 Jun; 274(6 Pt 1):L1066-72.
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320. Wolyniec WW, De Sanctis GT, Nabozny G, Torcellini C, Haynes N, Joetham A, Gelfand EW, Drazen JM, Noonan TC. Reduction of antigen-induced airway hyperreactivity and eosinophilia in ICAM-1-deficient mice. Am J Respir Cell Mol Biol. 1998 Jun; 18(6):777-85.
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321. Silverman EK, Chapman HA, Drazen JM, Weiss ST, Rosner B, Campbell EJ, O'DONNELL WJ, Reilly JJ, Ginns L, Mentzer S, Wain J, Speizer FE. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. Am J Respir Crit Care Med. 1998 Jun; 157(6 Pt 1):1770-8.
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322. Drazen J. Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors. Am J Respir Crit Care Med. 1998 Jun; 157(6 Pt 2):S233-7; discussion S247-8.
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323. Deykin A, Halpern O, Massaro AF, Drazen JM, Israel E. Expired nitric oxide after bronchoprovocation and repeated spirometry in patients with asthma. Am J Respir Crit Care Med. 1998 Mar; 157(3 Pt 1):769-75.
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324. Drazen JM. New directions in asthma drug therapy. Hosp Pract (Minneap). 1998 Feb 15; 33(2):25-6, 31-3, 36-8.
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325. Wechsler ME, Garpestad E, Flier SR, Kocher O, Weiland DA, Polito AJ, Klinek MM, Bigby TD, Wong GA, Helmers RA, Drazen JM. Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast. JAMA. 1998 Feb 11; 279(6):455-7.
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326. Haley KJ, Drazen JM. Inflammation and airway function in asthma: what you see is not necessarily what you get. Am J Respir Crit Care Med. 1998 Jan; 157(1):1-3.
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327. Wiggs BR, Hrousis CA, Drazen JM, Kamm RD. On the mechanism of mucosal folding in normal and asthmatic airways. J Appl Physiol. 1997 Dec; 83(6):1814-21.
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328. Drazen JM, Beier DR. The genetics of air pollution. Nat Genet. 1997 Dec; 17(4):365-6.
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329. Drazen JM, Silverman EK. Genetics of asthma: conference summary. Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 2):S69-71.
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330. De Sanctis GT, Drazen JM. Genetics of native airway responsiveness in mice. Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 2):S82-8.
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331. Fish JE, Peters SP, Chambers CV, McGeady SJ, Epstein KR, Boushey HA, Cherniack RM, Chinchilli VM, Drazen JM, Fahy JV, Hurd SS, Israel E, Lazarus SC, Lemanske RF, Martin RJ, Mauger EA, Sorkness C, Szefler SJ. An evaluation of colchicine as an alternative to inhaled corticosteriods in moderate asthma. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 1):1165-71.
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332. De Sanctis GT, Mehta S, Kobzik L, Yandava C, Jiao A, Huang PL, Drazen JM. Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice. Am J Physiol. 1997 Oct; 273(4 Pt 1):L883-8.
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333. O'Byrne PM, Israel E, Drazen JM. Antileukotrienes in the treatment of asthma. Ann Intern Med. 1997 Sep 15; 127(6):472-80.
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334. Mehta S, Drazen JM, Lilly CM. Endogenous nitric oxide and allergic bronchial hyperresponsiveness in guinea pigs. Am J Physiol. 1997 Sep; 273(3 Pt 1):L656-62.
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335. De Sanctis GT, Wolyniec WW, Green FH, Qin S, Jiao A, Finn PW, Noonan T, Joetham AA, Gelfand E, Doerschuk CM, Drazen JM. Reduction of allergic airway responses in P-selectin-deficient mice. J Appl Physiol. 1997 Sep; 83(3):681-7.
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336. De Sanctis GT, Itoh A, Green FH, Qin S, Kimura T, Grobholz JK, Martin TR, Maki T, Drazen JM. T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice. Nat Med. 1997 Apr; 3(4):460-2.
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337. Lilly CM, Nakamura H, Kesselman H, Nagler-Anderson C, Asano K, Garcia-Zepeda EA, Rothenberg ME, Drazen JM, Luster AD. Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J Clin Invest. 1997 Apr 1; 99(7):1767-73.
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338. Haley KJ, Drazen JM, Osathanondh R, Sunday ME. Comparison of the ontogeny of protein gene product 9.5, chromogranin A and proliferating cell nuclear antigen in developing human lung. Microsc Res Tech. 1997 Apr 1; 37(1):62-8.
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339. Serhan CN, Drazen JM. Antiinflammatory potential of lipoxygenase-derived eicosanoids: a molecular switch at 5 and 15 positions? J Clin Invest. 1997 Mar 15; 99(6):1147-8.
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340. Asano K, Nakamura H, Lilly CM, Klagsbrun M, Drazen JM. Interferon gamma induces prostaglandin G/H synthase-2 through an autocrine loop via the epidermal growth factor receptor in human bronchial epithelial cells. J Clin Invest. 1997 Mar 1; 99(5):1057-63.
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341. In KH, Asano K, Beier D, Grobholz J, Finn PW, Silverman EK, Silverman ES, Collins T, Fischer AR, Keith TP, Serino K, Kim SW, De Sanctis GT, Yandava C, Pillari A, Rubin P, Kemp J, Israel E, Busse W, Ledford D, Murray JJ, Segal A, Tinkleman D, Drazen JM. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest. 1997 Mar 1; 99(5):1130-7.
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342. Drazen JM. Pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors in the management of asthma. Pharmacotherapy. 1997 Jan-Feb; 17(1 Pt 2):22S-30S.
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343. Sobh JF, Lilly CM, Drazen JM, Jackson AC. Respiratory transfer impedance between 8 and 384 Hz in guinea pigs before and after bronchial challenge. J Appl Physiol. 1997 Jan; 82(1):172-81.
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344. Mehta S, Lilly CM, Rollenhagen JE, Haley KJ, Asano K, Drazen JM. Acute and chronic effects of allergic airway inflammation on pulmonary nitric oxide production. Am J Physiol. 1997 Jan; 272(1 Pt 1):L124-31.
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345. De Sanctis GT, Drazen JM. Genetics of airway responsiveness in the inbred mouse. Res Immunol. 1997 Jan; 148(1):73-9; discussion 79-83.
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346. Grasemann H, Drazen JM, Yandava CN. Protein sequence of the human neuronal nitric oxide synthase (Type I NOS): an error in the sequence database. Nitric Oxide. 1997; 1(6):441.
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347. Levy BD, Drazen JM, Serhan CN. Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA. Adv Exp Med Biol. 1997; 400B:611-5.
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348. Drazen JM, Weiss ST, Cooper D. Beta 2 adrenoceptor polymorphisms. Thorax. 1996 Nov; 51(11):1168.
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349. Roach JM, Muza SR, Rock PB, Lyons TP, Lilly CM, Drazen JM, Cymerman A. Urinary leukotriene E4 levels increase upon exposure to hypobaric hypoxia. Chest. 1996 Oct; 110(4):946-51.
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350. Drazen JM, Israel E, Boushey HA, Chinchilli VM, Fahy JV, Fish JE, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Sorkness C, Szefler SJ. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. N Engl J Med. 1996 Sep 19; 335(12):841-7.
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351. Asano K, Lilly CM, Drazen JM. Prostaglandin G/H synthase-2 is the constitutive and dominant isoform in cultured human lung epithelial cells. Am J Physiol. 1996 Jul; 271(1 Pt 1):L126-31.
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352. Mansour M, Karmilowicz M, Hawrylik SJ, Nalcerio B, Angilly J, Conklyn MJ, Lilly CM, Drazen JM, Lee SE, Auperin DD, De Wet JR, Cohan VL, Showell HJ, Danley DE. Production and characterization of guinea pig IL-5 in baculovirus-infected insect cells. Am J Physiol. 1996 Jun; 270(6 Pt 1):L1002-7.
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353. Massaro AF, Drazen JM. "Exhaled nitric oxide during exercise: site of release and modulation by ventilation and blood flow". J Appl Physiol. 1996 Jun; 80(6):1863-4.
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354. Kamada AK, Szefler SJ, Martin RJ, Boushey HA, Chinchilli VM, Drazen JM, Fish JE, Israel E, Lazarus SC, Lemanske RF. Issues in the use of inhaled glucocorticoids. The Asthma Clinical Research Network. Am J Respir Crit Care Med. 1996 Jun; 153(6 Pt 1):1739-48.
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355. Massaro AF, Mehta S, Lilly CM, Kobzik L, Reilly JJ, Drazen JM. Elevated nitric oxide concentrations in isolated lower airway gas of asthmatic subjects. Am J Respir Crit Care Med. 1996 May; 153(5):1510-4.
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356. Yager D, Martins MA, Feldman H, Kamm RD, Drazen JM. Acute histamine-induced flux of airway liquid: role of neuropeptides. J Appl Physiol. 1996 Apr; 80(4):1285-95.
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357. Israel E, Cohn J, Dubé L, Drazen JM. Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group. JAMA. 1996 Mar 27; 275(12):931-6.
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358. Lilly CM, Chapman RW, Sehring SJ, Mauser PJ, Egan RW, Drazen JM. Effects of interleukin 5-induced pulmonary eosinophilia on airway reactivity in the guinea pig. Am J Physiol. 1996 Mar; 270(3 Pt 1):L368-75.
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359. Drazen JM, Arm JP, Austen KF. Sorting out the cytokines of asthma. J Exp Med. 1996 Jan 1; 183(1):1-5.
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360. Asano K, Lilly CM, O'Donnell WJ, Israel E, Fischer A, Ransil BJ, Drazen JM. Diurnal variation of urinary leukotriene E4 and histamine excretion rates in normal subjects and patients with mild-to-moderate asthma. J Allergy Clin Immunol. 1995 Nov; 96(5 Pt 1):643-51.
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361. De Sanctis GT, Merchant M, Beier DR, Dredge RD, Grobholz JK, Martin TR, Lander ES, Drazen JM. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat Genet. 1995 Oct; 11(2):150-4.
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362. Fischer AR, McFadden CA, Frantz R, Awni WM, Cohn J, Drazen JM, Israel E. Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects. Am J Respir Crit Care Med. 1995 Oct; 152(4 Pt 1):1203-7.
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363. Massaro AF, Gaston B, Kita D, Fanta C, Stamler JS, Drazen JM. Expired nitric oxide levels during treatment of acute asthma. Am J Respir Crit Care Med. 1995 Aug; 152(2):800-3.
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364. Drazen JM, Turino GM. Progress at the interface of inflammation and asthma. Report of an ATS-sponsored workshop November, 1993. Am J Respir Crit Care Med. 1995 Jul; 152(1):386-7.
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365. Drazen JM, Evans JF, Stevens RL, Shipp MA. Inflammatory effector mechanisms in asthma. Am J Respir Crit Care Med. 1995 Jul; 152(1):403-7.
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366. Drazen JM, Israel E. Treatment of chronic stable asthma with drugs active on the 5-lipoxygenase pathway. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):319-20.
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367. Lilly CM, Hall AE, Rodger IW, Kobzik L, Haley KJ, Drazen JM. Substance P-induced histamine release in tracheally perfused guinea pig lungs. J Appl Physiol. 1995 Apr; 78(4):1234-41.
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368. Rothenberg ME, Luster AD, Lilly CM, Drazen JM, Leder P. Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung. J Exp Med. 1995 Mar 1; 181(3):1211-6.
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369. Yager D, Kamm RD, Drazen JM. Airway wall liquid. Sources and role as an amplifier of bronchoconstriction. Chest. 1995 Mar; 107(3 Suppl):105S-110S.
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370. Lilly CM, Bai TR, Shore SA, Hall AE, Drazen JM. Neuropeptide content of lungs from asthmatic and nonasthmatic patients. Am J Respir Crit Care Med. 1995 Feb; 151(2 Pt 1):548-53.
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371. Coleman RA, Eglen RM, Jones RL, Narumiya S, Shimizu T, Smith WL, Dahlén SE, Drazen JM, Gardiner PJ, Jackson WT, et al. Prostanoid and leukotriene receptors: a progress report from the IUPHAR working parties on classification and nomenclature. Adv Prostaglandin Thromboxane Leukot Res. 1995; 23:283-5.
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372. Drazen JM, Gaston B, Shore SA. Chemical regulation of pulmonary airway tone. Annu Rev Physiol. 1995; 57:151-70.
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373. Drazen J. Clinical studies with agents active on the 5-lipoxygenase pathway. Allergy. 1995; 50(22 Suppl):22-6.
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374. Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Rubin P, Cohn J, White MV, Igarashi Y, Kaliner MA, Drazen JM, et al. Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 1):1046-56.
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375. Yager D, Cloutier T, Feldman H, Bastacky J, Drazen JM, Kamm RD. Airway surface liquid thickness as a function of lung volume in small airways of the guinea pig. J Appl Physiol. 1994 Nov; 77(5):2333-40.
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376. Goodman DE, Israel E, Rosenberg M, Johnston R, Weiss ST, Drazen JM. The influence of age, diagnosis, and gender on proper use of metered-dose inhalers. Am J Respir Crit Care Med. 1994 Nov; 150(5 Pt 1):1256-61.
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377. Asano K, Chee CB, Gaston B, Lilly CM, Gerard C, Drazen JM, Stamler JS. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21):10089-93.
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378. Israel E, Drazen JM. Treating mild asthma--when are inhaled steroids indicated? N Engl J Med. 1994 Sep 15; 331(11):737-9.
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379. Oettgen HC, Martin TR, Wynshaw-Boris A, Deng C, Drazen JM, Leder P. Active anaphylaxis in IgE-deficient mice. Nature. 1994 Aug 4; 370(6488):367-70.
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380. Lilly CM, Kobzik L, Hall AE, Drazen JM. Effects of chronic airway inflammation on the activity and enzymatic inactivation of neuropeptides in guinea pig lungs. J Clin Invest. 1994 Jun; 93(6):2667-74.
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381. Lilly CM, Besson G, Israel E, Rodger IW, Drazen JM. Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs. Am J Respir Crit Care Med. 1994 May; 149(5):1175-9.
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382. Vasconcellos CA, Allen PG, Wohl ME, Drazen JM, Janmey PA, Stossel TP. Reduction in viscosity of cystic fibrosis sputum in vitro by gelsolin. Science. 1994 Feb 18; 263(5149):969-71.
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383. Gaston B, Drazen JM, Jansen A, Sugarbaker DA, Loscalzo J, Richards W, Stamler JS. Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro. J Pharmacol Exp Ther. 1994 Feb; 268(2):978-84.
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384. Gaston B, Drazen JM, Loscalzo J, Stamler JS. The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med. 1994 Feb; 149(2 Pt 1):538-51.
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385. Drazen JM, Lilly CM, Sperling R, Rubin P, Israel E. Role of cysteinyl leukotrienes in spontaneous asthmatic responses. Adv Prostaglandin Thromboxane Leukot Res. 1994; 22:251-62.
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386. Martin TR, Cohen ML, Drazen JM. Serotonin-induced pulmonary responses are mediated by the 5-HT2 receptor in the mouse. J Pharmacol Exp Ther. 1994 Jan; 268(1):104-9.
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387. Israel E, Rubin P, Kemp JP, Grossman J, Pierson W, Siegel SC, Tinkelman D, Murray JJ, Busse W, Segal AT, Fish J, Kaiser HB, Ledford D, Wenzel S, Rosenthal R, Cohn J, Lanni C, Pearlman H, Karahalios P, Drazen JM. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med. 1993 Dec 1; 119(11):1059-66.
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388. Gaston B, Reilly J, Drazen JM, Fackler J, Ramdev P, Arnelle D, Mullins ME, Sugarbaker DJ, Chee C, Singel DJ, et al. Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways. Proc Natl Acad Sci U S A. 1993 Dec 1; 90(23):10957-61.
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389. Israel E, Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Shapiro J, Cohn J, Rubin P, Drazen JM. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis. 1993 Dec; 148(6 Pt 1):1447-51.
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390. Levy BD, Bertram S, Tai HH, Israel E, Fischer A, Drazen JM, Serhan CN. Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA. Lipids. 1993 Dec; 28(12):1047-53.
  View in: PubMed